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To get the maximum benefit from your medication, it is advisable not to drink excessive amounts of alcohol before taking this medication. A double-blind, placebo-controlled exercise stress trial evaluated 144 patients with erectile dysfunction and chronic stable angina who regularly received anti-anginal medicinal products (except nitrates). The results demonstrated no clinically relevant differences between sildenafil and placebo in time to limiting angina. Sildenafil is a potent and selective inhibitor of cGMP specific phosphodiesterase type 5 (PDE5) in the corpus cavernosum, where PDE5 is responsible for degradation of cGMP. Sildenafil has no direct relaxant effect on isolated human corpus cavernosum but potently enhances the relaxant effect of NO on this tissue. When the NO/cGMP pathway is activated, as occurs with sexual stimulation, inhibition of PDE5 by sildenafil results in increased corpus cavernosum levels of cGMP.
If your doctor recommends Viagra for you, they will prescribe the dosage that’s right for you. Always follow the dosage that your doctor prescribes for you. Keep in mind that meals high in fat may cause Viagra to take longer than usual to start working.
If you experience any serious side effects, you must stop taking Viagra and go to A&