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Sildenafil metabolism is principally mediated by the cytochrome P450 (CYP) isoforms 3A4 (major route) and Kamagra 2C9 (minor route). Therefore, inhibitors of these isoenzymes may reduce sildenafil clearance and inducers of these isoenzymes may increase sildenafil clearance. Dosage adjustments are not required in elderly patients (≥ 65 years old). If you have questions about the safety of using Viagra while breastfeeding, talk with your doctor. If you have questions about the safety of Viagra use during pregnancy, talk with your doctor. Viagra tablets should be stored at room temperature between 68oF and 77°F (20oC and 25°C).

Make sure that you inform them if you notice any side effects or if your treatment isn’t working like it should. There are four different Sildenafil dosages prescribed for the treatment of erectile dysfunction. The different Viagra strengths give the option to raise or lower the amount of active ingredient (sildenafil citrate), depending on how your body reacts to the treatment. Viagra has been studied in four main studies including 1,690 men aged 19 to 87 years, where it was compared with placebo (a dummy treatment) for between 12 and 26 weeks. Two of these studies used fixed doses (patients allocated to 25, 50 or 100 mg) and two studies were flexible (patients started on 25 mg and could be moved to 50 or 100 mg depending on their response). In addition, there were studies in patients with spinal cord injury and with diabetes.

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